Seminar über aktuelle Fragen zur Dynamik komplexer Fluide: Size Coordination in Animals and the Statistical Physics of Growing Tissues

Seminar über aktuelle Fragen zur Dynamik komplexer Fluide

  • Datum: 08.02.2019
  • Uhrzeit: 10:15 - 11:15
  • Vortragende(r): Ojan Khatib-Damavandi
  • University of Michigan, Ann Arbor, USA
  • Ort: Max-Planck-Institut für Dynamik und Selbstorganisation (MPIDS)
  • Raum: SR 0.77
  • Gastgeber: MPIDS/DCF
  • Kontakt:
One of the major questions in biology is how organs know when to stop growing and how animals coordinate growth of their organs to ensure proper body proportions. In this talk, we first discuss coordination between left and right organs (like fruit fly wings) via chemical signaling. We show analytically that there are limits to the ability of the signal to ensure successful left/right symmetry, suggesting that organ sizes are primarily set autonomously. Inspired by this conclusion, we look at noisy growth of individual tissues subject to mechanical feedbacks and show that even the simplest model of tissue growth exhibits a surprisingly rich behavior. For instance, we find that the growth displays power law correlations, and soft modes that lead to large variations in the size of marked clones of cells.
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