Talk

Talk: How do cells move? The Filament Based Lamellipodium Model in the limit of short filaments

  • Date: Nov 16, 2017
  • Time: 11:00 - 12:00
  • Speaker: Sarah Henze, M.Sc.
  • University of Vienna, Faculty of Mathematics
  • Location: Max-Planck-Institut für Dynamik und Selbstorganisation (MPIDS)
  • Room: 1.51 (Bernsteinzimmer)
  • Host: MPIDS
  • Contact: armita@ds.mpg.de
One mathematical model for the dynamics of the actin filament network in the lamellipodium of migrating cells is the Filament Based Lamellipodium Model (FBLM) – a two-dimensional, anisotropic two-phase continuum model. In this thesis, we aim to propose a simplified version of this model, by considering rigid filaments of equal length. We then perform a formal asymptotic dimension reduction limit in the regime of small filaments. The resulting one-dimensional system describes the processes along the cell periphery.

Picture: By courtesy of Angelika Manhart.
 
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